Some freaks of nature are fun and interesting. Take 4-leaf clovers,  for example. It is estimated that there are 10,000 3-leaf clovers to  every 4-leaf clover, making the 4-leafers a bit of a stand-our freak in  the clover field. Clovers can also have 5, 6 and even more leaves. The  record, in fact, appears to be 
21 leaves on one clover (I  recently found a 6-leaf clover while visiting Michigan and have added  it to my collection of 4 and 5 leaf specimens.) It is debated  whether extra leaflets on clovers are  caused genetically or  environmentally. Their relative rarity suggests a possible recessive  gene, a somatic mutation or a developmental error of environmental  causes.
Variegated plants  are another form of nature freak. In layman’s terms, variegations in  plants are created when chlorophyll (the substance that makes leaves  green) is absent in part of the leaf. The variations in color are caused  by whatever pigments are present in the leaf where chlorophyll is  absent. White areas in foliage means no chlorophyll and nothing to  replace it. Yellow patches means no chlorophyll but the presence of  xanthophyll. Other colors are created by the presence of a substance  called anthocyanins in combination with either chlorophyll or  xanthophyll.
Of course, scientists, horticulturists and others out to make a buck  have learned to imitate these natural mutations so that four-leaf  clovers and variegated cultivars of almost every plant species are  readily available.
But did you know that the chemicals you use in your garden could also  be creating freaks of nature? But they aren’t the kind of freaks that  add fun or beauty to the world. Scientific studies have shown that  landscape chemicals which find their way into local waterways may be  causing deformities in fish, frogs and other animal species.
One way that these deformities show up is by creating intersex fish.  Intersex is a condition in which fish may exhibit characteristics of  both sexes, such as 
male fish producing eggs. Intersex specimens of smallmouth bass and other fish have been found inmany states, including  both Virginia and Maryland.
Frogs and other amphibians also seem to be suffering the effects of pollutants. 
Frogs with deformed limbs  have been found in almost every state and many amphibian populations  are suffering. The problem is so extensive that the U.S. Fish and  Wildlife Service declared 2008 the Year of the Frog to help emphasize  what everyday citizens can do to help correct the problem.
Here are some steps you can take, excerpted from the U.S. Fish and Wildlife Document 
Homeowner’s Guide to Protecting Frogs: Lawn and Garden Care
You may not think that you can make a difference, but caring for your lawn in an environmentally sensible way can have a bigger impact than you might think.  
You can help keep the environment clean and the frogs healthy by following these simple tips. If everyone does their part to protect the environment, all types of fish and wildlife, including frogs, will enjoy a cleaner, healthier environment. 
Choose non-chemical weed controls whenever possible: 
Mulching, spading, hoeing and pulling up weeds are good ways to avoid weed growth rather than applying weed killer.  
Minimize fertilizer use: 
Overfertilization is a common problem. Fertilizing more than the recommended rate does not help plants grow better and often harms them. In addition, excess fertilizer will likely wash into streams and rivers and may lead to amphibian deformities and deaths. Researchers at Oregon State University recently discovered that even low levels of nitrates (a compound found in fertilizers) are enough to kill some species of amphibians. Help prevent pollution from fertilizer by taking these actions: 
* Leave the grass clippings from mowing to decompose on your lawn (feeding your lawn this way is equal to fertilizing it once or twice a year).
* Use 
compost in your garden to develop healthy soils and reduce the need for chemical fertilizers. 
* Have your soil tested to find out exactly what nutrients it needs in order to avoid applying unnecessary fertilizers. Your County Agricultural Extension Service will test your soil for a reasonable fee.
 
* Use 
organic fertilizers rather than synthetic ones. Organic fertilizers release more slowly into the environment and create healthier soils.
* Apply fertilizer when the soil is moist and then lightly water. This will help the fertilizer move into the root zone instead of blowing or washing away. However, be sure to check the weather forecast in order to avoid applying fertilizers immediately before a heavy rain which may wash the fertilizers into the nearby streams.
* Calibrate your applicator to make sure you apply the correct amount of fertilizer.  
* Minimize the attraction of pests such as rats, therefore reducing the need for pesticides, by moving wood piles away from the house and clearing away litter and garbage.
* Plant native grasses, shrubs, and trees. Native plants are often hardier than non-native plants and less susceptible to pests and disease.
* Put an assortment of plants in your yard to increase biological diversity and encourage a variety of beneficial organisms that provide natural pest control.
* Rotate the plants in your annual garden. Changing the type of plants you grow each year makes it harder for pests dependent on a certain type of plant to become established, and therefore, eliminates the need for pesticides.
* Grow plants that are natural insect repellents, such as lemon balm, among your flowers and vegetables to help keep unwanted insects away.  
Other Suggestions: 
* Keep litter, pet wastes, leaves, and debris 
out of street gutters and storm drains. These outlets drain directly into lakes, streams, rivers, and wetlands. Pet wastes contain bacteria and viruses that can threaten fish, wildlife, and people.
* Never dump oil, antifreeze, or other household chemicals into storm drains or sewers, down the drain of your sink, or into the toilet. Contact your local Solid Waste Management Office to find out how to 
dispose of these materials properly.
One thing that was not mentioned in the article is the benefit of using 
rain barrels, 
permeable surfaces,  rain gardens and other methods to help cut down on stormwater runoff  which is what washes all of these chemicals into the waterways in the  first place.
Taking any of these steps will help you do your part to keep the planet a little less freaky!